|
Colorectal Carcinoma
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Two patients with KRAS-mutated CRC showed the same mutation in PPL in the same specimen (one serrated change NOS and one TSA with high-grade dysplasia).
|
30679085 |
2019 |
|
Gerstmann-Straussler-Scheinker Disease
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
Here we have performed systematic studies of purified resPrP<sup>D</sup> species extracted from GSS cases with the A117V (GSS<sup>A117V</sup>) and F198S (GSS<sup>F198S</sup>) PrP gene mutations.
|
31142381 |
2019 |
|
Tumor Cell Invasion
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
Decreased EGFR phosphorylation is associated with reduced EGFR protein levels in the presence of TSA, which inactivates Arf1 and eventually inhibits invasion in HNSCC cells.
|
30777099 |
2019 |
|
Scrub Typhus
|
0.060 |
Biomarker
|
disease |
BEFREE |
We conducted this study to describe the phylogenetic analysis of the 56-kDa type-specific antigen (TSA) gene of Orientia tsutsugamushi associated with PCR positive cases of scrub typhus.
|
31469878 |
2019 |
|
Scrub Typhus
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
Two cases of scrub typhus reported in the Tohoku region during 2011-2012 also involved the same 56-kDa TSA gene sequence.
|
31087695 |
2019 |
|
Carcinogenesis
|
0.060 |
Biomarker
|
phenotype |
BEFREE |
In addition, Prx1 and Prx2 are able to bind to a diversity of interaction partners to regulate other various cellular processes in cancer (i.e., regulation of the protein redox status, cell growth, apoptosis, and tumorigenesis).
|
31185618 |
2019 |
|
Carcinogenesis
|
0.060 |
Biomarker
|
phenotype |
BEFREE |
In conclusion, these findings demonstrate that Prdx2 may participate in the carcinogenesis and development of gastric cancer.
|
31807984 |
2019 |
|
Chondrosarcoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
A significant decrease in ALDHhigh CSCs was observed following treatment of chondrosarcoma JJ012 cells with PRP‑1.
|
31180539 |
2019 |
|
Malignant neoplasm of stomach
|
0.050 |
Biomarker
|
disease |
BEFREE |
In conclusion, these findings demonstrate that Prdx2 may participate in the carcinogenesis and development of gastric cancer.
|
31807984 |
2019 |
|
Malignant neoplasm of stomach
|
0.050 |
Biomarker
|
disease |
BEFREE |
Inhibition of peroxiredoxin 2 suppresses Wnt/β-catenin signaling in gastric cancer.
|
30879771 |
2019 |
|
Stomach Carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
In conclusion, these findings demonstrate that Prdx2 may participate in the carcinogenesis and development of gastric cancer.
|
31807984 |
2019 |
|
Stomach Carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
Inhibition of peroxiredoxin 2 suppresses Wnt/β-catenin signaling in gastric cancer.
|
30879771 |
2019 |
|
Malignant tumor of colon
|
0.040 |
Biomarker
|
disease |
BEFREE |
<b>Purpose:</b> We have previously reported that PRDX2 plays an oncogenic role in colon cancer.
|
31388312 |
2019 |
|
Diphtheria
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
This study assessed a pediatric mixed hexavalent diphtheria (D)-tetanus (T)-acellular pertussis (aP)-inactivated poliovirus (IPV)-hepatitis B (HB)-Haemophilus influenzae b [polyribosylribitol phosphate (PRP-T)]-pentavalent (DTaP-IPV//PRP-T)-hexavalent primary series schedule followed by a pentavalent booster.
|
30408001 |
2019 |
|
Hepatitis B
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
This study assessed a pediatric mixed hexavalent diphtheria (D)-tetanus (T)-acellular pertussis (aP)-inactivated poliovirus (IPV)-hepatitis B (HB)-Haemophilus influenzae b [polyribosylribitol phosphate (PRP-T)]-pentavalent (DTaP-IPV//PRP-T)-hexavalent primary series schedule followed by a pentavalent booster.
|
30408001 |
2019 |
|
Disorder of tendon
|
0.040 |
Biomarker
|
group |
BEFREE |
We hypothesized that STR/PRP would be a safe and effective treatment for lateral epicondylar tendinopathy.
|
30487054 |
2019 |
|
Disorder of tendon
|
0.040 |
GeneticVariation
|
group |
BEFREE |
Twenty patients with a diagnosis of patellar tendinopathy with imaging changes (tendon thickening and disruption of the intratendinous substance at the proximal portion of the patellar tendon) will be randomised in a 1:1 ratio to receive a local injection of either bone-marrow autologous mesenchymal stem cells (MSC), isolated and cultured under GMP at The Institute of Biology and Molecular Genetics (IBGM) (Spain) or P-PRP.
|
31842921 |
2019 |
|
Malignant neoplasm of lung
|
0.040 |
Biomarker
|
disease |
BEFREE |
Taken together, our results elucidate the roles and mechanisms of Prdx2 S-nitrosylation at Cys51 and Cys172 sites in lung cancer cells apoptosis and this finding provides an effective lung cancer treatment strategy for managing aberrant Prdx2 activity in lung cancers.
|
30988280 |
2019 |
|
Carcinoma of lung
|
0.040 |
Biomarker
|
disease |
BEFREE |
S-nitrosylation of the Peroxiredoxin-2 promotes S-nitrosoglutathione-mediated lung cancer cells apoptosis via AMPK-SIRT1 pathway.
|
30988280 |
2019 |
|
Colon Carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
<b>Purpose:</b> We have previously reported that PRDX2 plays an oncogenic role in colon cancer.
|
31388312 |
2019 |
|
Primary malignant neoplasm of lung
|
0.040 |
Biomarker
|
disease |
BEFREE |
S-nitrosylation of the Peroxiredoxin-2 promotes S-nitrosoglutathione-mediated lung cancer cells apoptosis via AMPK-SIRT1 pathway.
|
30988280 |
2019 |
|
Tendinopathy
|
0.040 |
Biomarker
|
disease |
BEFREE |
We hypothesized that STR/PRP would be a safe and effective treatment for lateral epicondylar tendinopathy.
|
30487054 |
2019 |
|
Tendinopathy
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
Twenty patients with a diagnosis of patellar tendinopathy with imaging changes (tendon thickening and disruption of the intratendinous substance at the proximal portion of the patellar tendon) will be randomised in a 1:1 ratio to receive a local injection of either bone-marrow autologous mesenchymal stem cells (MSC), isolated and cultured under GMP at The Institute of Biology and Molecular Genetics (IBGM) (Spain) or P-PRP.
|
31842921 |
2019 |
|
Influenza
|
0.030 |
Biomarker
|
disease |
BEFREE |
This study assessed a pediatric mixed hexavalent diphtheria (D)-tetanus (T)-acellular pertussis (aP)-inactivated poliovirus (IPV)-hepatitis B (HB)-Haemophilus influenzae b [polyribosylribitol phosphate (PRP-T)]-pentavalent (DTaP-IPV//PRP-T)-hexavalent primary series schedule followed by a pentavalent booster.
|
30408001 |
2019 |
|
Esophageal carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
The expression levels of ZNF667-AS1 and ZNF667 were significantly reversed by treatment with 5-Aza-dC and TSA in esophageal cancer cell lines.
|
31804468 |
2019 |