PRDX2, peroxiredoxin 2, 7001

N. diseases: 243; N. variants: 2
Disease: Chondrosarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008479
Disease: Chondrosarcoma
Chondrosarcoma 		0.050 Biomarker disease BEFREE A significant decrease in ALDHhigh CSCs was observed following treatment of chondrosarcoma JJ012 cells with PRP‑1. 31180539 2019
CUI: C0008479
Disease: Chondrosarcoma
Chondrosarcoma 		0.050 AlteredExpression disease BEFREE TLR1/2, TLR6 and MUC5B were downregulated in human chondrosarcoma and upregulated in dose-response manner upon PRP-1 treatment. 29138803 2018
CUI: C0008479
Disease: Chondrosarcoma
Chondrosarcoma 		0.050 Biomarker disease BEFREE PRP-1 had strong inhibitory effect on viability of chondrosarcoma and multilineage induced multipotent adult cells (embryonic primitive cell type). 26094604 2015
CUI: C0008479
Disease: Chondrosarcoma
Chondrosarcoma 		0.050 Biomarker disease BEFREE Regulation of onco and tumor suppressor MiRNAs by mTORC1 inhibitor PRP-1 in human chondrosarcoma. 24178909 2014
CUI: C0008479
Disease: Chondrosarcoma
Chondrosarcoma 		0.050 Biomarker disease BEFREE The fact that addition of PRP-1 caused drastic inactivation of Myc-luc response element to the control level in human chondrosarcoma JJ012 cell line prompts to investigate further this neuropeptides powerful antioncogenic potential, opening up possibilities to consider PRP-1 as a potential therapeutic tool for chondrosarcoma treatment. 18612811 2009