TEK, TEK receptor tyrosine kinase, 7010

N. diseases: 300; N. variants: 17
Disease: Hemangioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018916
Disease: Hemangioma
Hemangioma 		0.050 Biomarker disease BEFREE Treatment of Tie2/PyMT transgenic mice with the PP2A activator FTY720 significantly delayed the occurrence of hemangioma. 26308070 2015
CUI: C0018916
Disease: Hemangioma
Hemangioma 		0.050 AlteredExpression disease BEFREE In addition, we showed that Tie2 mRNA expression in spinal VMs was similar to soft tissue VMs, but obviously lower than infant hemangiomas (P<0.01). 26115772 2015
CUI: C0018916
Disease: Hemangioma
Hemangioma 		0.050 AlteredExpression disease BEFREE Western blot analysis showed increased Tie2 expression in hemangioma samples compared with normal ECs. 22996814 2013
CUI: C0018916
Disease: Hemangioma
Hemangioma 		0.050 Biomarker disease BEFREE We also demonstrate that inhibition of tie-2 signaling with a soluble tie-2 receptor decreases bEnd.3 hemangioma growth in vivo. 16741507 2006
CUI: C0018916
Disease: Hemangioma
Hemangioma 		0.050 AlteredExpression disease BEFREE We found Tie2 mRNA and protein up-regulated with a concomitant increase in cellular responsiveness to Ang1 in most hemangioma-derived endothelial cells. 11733376 2001
CUI: C0018916
Disease: Hemangioma
Hemangioma 		0.050 AlteredExpression disease LHGDN We found Tie2 mRNA and protein up-regulated with a concomitant increase in cellular responsiveness to Ang1 in most hemangioma-derived endothelial cells. 11733376 2001