TEK, TEK receptor tyrosine kinase, 7010

N. diseases: 300; N. variants: 17
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018923
Disease: Hemangiosarcoma
Hemangiosarcoma
0.310 Biomarker disease CTD_human Carcinogenic susceptibility of rasH2 mice to troglitazone. 17569031 2007
CUI: C0018923
Disease: Hemangiosarcoma
Hemangiosarcoma
0.310 Biomarker disease BEFREE Murine endothelial cells (ECs) overexpressing this G833DTie2 receptor exhibited an increase in cell proliferation at low serum concentrations and angiosarcomas developed in nude mice, whereas cells overexpressing either wild-type Tie2 or Q837HTie2 failed to elicit these responses. 15377998 2004