TEK, TEK receptor tyrosine kinase, 7010

N. diseases: 300; N. variants: 17
Disease: Carcinogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 Biomarker phenotype BEFREE VEGFR-2, Tie-2, and EphB4 are essential for both angiogenesis and tumorigenesis. 30503935 2019
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 Biomarker phenotype BEFREE Receptor tyrosine kinases (RTKs), especially VEGFR-2, TIE-2, and EphB4, play a crucial role in both angiogenesis and tumorigenesis. 29285210 2017
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 Biomarker phenotype BEFREE VEGFR-2, TIE-2, and EphB4 are essential for both angiogenesis and tumorigenesis. 29032031 2017
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 Biomarker phenotype BEFREE Angiopoietin (Ang) -1 and -2 and their receptor Tie2 play critical roles in regulating angiogenic processes during development, homeostasis, tumorigenesis, inflammation and tissue repair. 24404127 2014
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 AlteredExpression phenotype BEFREE Although Tie-2 and Ang-1 are not differentially expressed in pancreatic tumors, Ang-2 gene and gene product are overexpressed, suggesting a significant role for Ang-2 in pancreatic tumorigenesis. 15501112 2004
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.060 Biomarker phenotype BEFREE However, the role of Tie2 receptor in hepatic oncogenesis is unknown. 11915032 2002