TERT, telomerase reverse transcriptase, 7015

N. diseases: 703; N. variants: 97
Disease: Thyroid carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma 		0.400 Biomarker disease BEFREE We investigated the association between TERT promoter mutations and recurrence in a prospective series of 173 intermediate- to high-risk patients with thyroid cancer. 30648628 2019
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma 		0.400 Biomarker disease BEFREE The aim of this study was to search for novel TERT promoter mutations and additional mechanisms of TERT activation in thyroid cancer. 31408918 2019
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma 		0.400 Biomarker disease BEFREE LncRNA FOXD2-AS1 Functions as a Competing Endogenous RNA to Regulate TERT Expression by Sponging miR-7-5p in Thyroid Cancer. 31024447 2019
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma 		0.400 GeneticVariation disease BEFREE Recently, telomerase reverse transcriptase (<i>TERT</i>) gene promoter (<i>TERTp</i>) mutations (C228T and C250T) were reported at high frequency in TC cell lines and tumor biopsies. 31549911 2019
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma 		0.400 GeneticVariation disease BEFREE The association between telomerase reverse transcriptase (TERT) promoter mutations and some clinical behaviors in thyroid cancer remains controversial and requires additional investigation. 31655978 2020