TERT, telomerase reverse transcriptase, 7015

N. diseases: 703; N. variants: 97
Disease: T-Cell Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma 		0.020 GeneticVariation disease BEFREE To assess telomerase as a cancer therapeutic target and determine adaptive mechanisms to telomerase inhibition, we modeled telomerase reactivation and subsequent extinction in T cell lymphomas arising in Atm(-/-) mice engineered with an inducible telomerase reverse transcriptase allele. 22341440 2012
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma 		0.020 Biomarker disease BEFREE In this study, we aimed to use the Marek's disease virus (MDV) T-cell lymphoma model to evaluate TERT regulation by splicing during lymphomagenesis in vivo, from the start point to tumor establishment. 20964812 2010