TERT, telomerase reverse transcriptase, 7015

N. diseases: 703; N. variants: 97
Disease: Acral Lentiginous Malignant Melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0346037
Disease: Acral Lentiginous Malignant Melanoma
Acral Lentiginous Malignant Melanoma 		0.320 Biomarker disease BEFREE These findings provide insight into the role of <i>TERT</i> in ALM tumorigenesis and reveal preliminary evidence that TERT inhibition represents a potential therapeutic strategy in ALM. 28373299 2017
CUI: C0346037
Disease: Acral Lentiginous Malignant Melanoma
Acral Lentiginous Malignant Melanoma 		0.320 GeneticVariation disease BEFREE TERT (human telomerase reverse transcriptase) promoter mutations have being described as recurrent in melanomas and infrequent in ALM, but their real incidence and clinical relevance is unclear. 26709572 2016
CUI: C0346037
Disease: Acral Lentiginous Malignant Melanoma
Acral Lentiginous Malignant Melanoma 		0.320 GenomicAlterations disease CGI