|
IMMUNODEFICIENCY 46
|
0.700 |
Biomarker
|
disease |
CTD_human |
|
|
|
|
IMMUNODEFICIENCY 46
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
|
|
|
|
Combined immunodeficiency
|
0.400 |
CausalMutation
|
disease |
CLINVAR |
|
|
|
|
Anemia
|
0.200 |
Biomarker
|
disease |
HPO |
|
|
|
|
Immunologic Deficiency Syndromes
|
0.110 |
Biomarker
|
group |
HPO |
|
|
|
|
Neutropenia
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
|
Chronic diarrhea
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
|
Intermittent thrombocytopenia
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
|
Recurrent sinopulmonary infections
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
|
Decreased antibody level in blood
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
|
Iron deficiency
|
0.100 |
Biomarker
|
disease |
BEFREE |
<b>Background:</b> Total-body iron stores (TBI), which are calculated from serum ferritin and soluble transferrin receptor concentrations, can be used to assess the iron status of populations in the United States.<b>Objective:</b> This analysis, developed to support workshop discussions, describes the distribution of TBI and the prevalence of iron deficiency (ID) and ID anemia (IDA) among toddlers, nonpregnant females, and pregnant females.<b>Design:</b> We analyzed data from NHANES; toddlers aged 12-23 mo (NHANES 2003-2010), nonpregnant females aged 15-49 y (NHANES 2007-2010), and pregnant females aged 12-49 y (NHANES 1999-2010).
|
29070559 |
2017 |
|
Tumor Progression
|
0.040 |
AlteredExpression
|
phenotype |
BEFREE |
<b>Conclusion:</b> Though TfR1 was overexpressed in colorectal cancer tissues, there was evidence that downregulation of TfR1 could promote cancer progression.
|
31372038 |
2019 |
|
Lung diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
<b>Conclusions:</b> Taken together, these data highlight how CD71 delineates AM subsets that play distinct roles in IPF and furthermore show that CD71<sup>-</sup> AMs may be an important pathogenic component of fibrotic lung disease.
|
31051082 |
2019 |
|
Idiopathic Pulmonary Fibrosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
<b>Measurements and Main Results:</b> There was a distinct increase in proportions of AMs lacking CD71 in patients with IPF compared with healthy control subjects.
|
31051082 |
2019 |
|
Colorectal Carcinoma
|
0.340 |
AlteredExpression
|
disease |
BEFREE |
<b>Results:</b> TfR1 expression was higher in CRC tissues than in normal tissues (57.2% vs 22.9%, <i>P</i>＜0.001).
|
31372038 |
2019 |
|
Septicemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
<b>Results:</b> Our analysis revealed that several markers could be useful for sepsis diagnosis, such as CD45RA, CD45RO, or CD71 on T cells; HLA-DR on NKT or classic monocytes, and TREM-1 on non-classic monocytes or neutrophils.
|
31537145 |
2019 |
|
Sepsis
|
0.010 |
Biomarker
|
disease |
BEFREE |
<b>Results:</b> Our analysis revealed that several markers could be useful for sepsis diagnosis, such as CD45RA, CD45RO, or CD71 on T cells; HLA-DR on NKT or classic monocytes, and TREM-1 on non-classic monocytes or neutrophils.
|
31537145 |
2019 |
|
Iron deficiency
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
2 and 6 μm ELT increased Tfr1 and Slc11a2 (iron-responsive genes involved in neuronal iron uptake) mRNA levels, indicating neuronal ID.
|
28005311 |
2017 |
|
HEMOCHROMATOSIS, TYPE 1
|
0.100 |
Biomarker
|
disease |
BEFREE |
Hemochromatosis (HFE) and transferrin receptor-1 (TFRC1) genes in sporadic porphyria cutanea tarda (sPCT).
|
11929045 |
2002 |
|
Hemochromatosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Hemochromatosis and transferrin receptor gene polymorphisms in chronic hepatitis C: impact on iron status, liver injury and HCV genotype.
|
14557859 |
2003 |
|
HEMOCHROMATOSIS, TYPE 1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Hemochromatosis and transferrin receptor gene polymorphisms in chronic hepatitis C: impact on iron status, liver injury and HCV genotype.
|
14557859 |
2003 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase.
|
15342917 |
2004 |
|
Precursor B-cell lymphoblastic leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
B-cell acute lymphoblastic leukemia (B-ALL) expressed low levels of CD71 on leukemic cells, significantly lower than AML, mixed phenotype acute leukemia (MPAL) and normal bone marrow blasts (p < 0.05).
|
23962073 |
2014 |
|
Brain Neoplasms
|
0.060 |
Biomarker
|
group |
BEFREE |
Brain tumor-targeted therapy by systemic delivery of siRNA with Transferrin receptor-mediated core-shell nanoparticles.
|
27374198 |
2016 |
|
Iron deficiency
|
0.100 |
Biomarker
|
disease |
BEFREE |
Iron deficiency was quantifies as the serum transferrin receptor / ferritin index, with a cut-off level of 1.5.
|
28421565 |
2017 |