|
Anemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
These observations emphasize the coordination of mitochondrial and CD71 clearance in erythroid terminal maturation and offer new insights into a role for mitochondrial degeneration in the pathogenesis of some MDS-associated anemia.
|
30050123 |
2019 |
|
Anemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Soluble transferrin receptor/log ferritin index was significantly higher in iron deficiency anemia (median: 1.76) than in anemia of chronic disease (median: 0.55), anemia of chronic disease with iron deficiency (median: 0.68) or patients without anemia (median: 0.72).
|
30538074 |
2019 |
|
Anemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
In cost constraints settings, a simple investigation like Ret He alone or with serum ferritin can help us to diagnose and differentiate between the different types of anemia accompanying rheumatological disorders without doing other serum iron studies and expensive tests like transferrin receptor protein which are not readily available.
|
30968565 |
2019 |
|
Anemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Here, we evaluated potential associations of tryptophan, kynurenine, and kynurenic acid with indicators of iron metabolism (i.e., mean corpuscular volume, mean corpuscular haemoglobin, ferritin, transferrin saturation, serum iron, transferrin, soluble transferrin receptor, reticulocyte haemoglobin) and haemoglobin in 430 individuals grouped by the presence or absence of iron deficiency or anaemia.
|
31601941 |
2019 |
|
Anemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Using the soluble transferrin receptor index the type of anemia was determined.
|
29668567 |
2018 |
|
Anemia
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
Transferrin receptor 1 (TfR1), which is highly expressed in piglets with anemia, may play a role in TGEV infection.
|
30342530 |
2018 |
|
Anemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
We tested associations between these measures and serum concentrations of retinol, β-carotene, ferritin, soluble transferrin receptor, and hemoglobin (Hb <11.0 or 11.5 g/dL were used to define anemia, depending on age), as well as anthropometric indexes, with the use multilevel mixed-effects models.
|
29924320 |
2018 |
|
Anemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Recently reports showed that TFR1 involved in many kinds of diseases including anemia, neurodegenerative diseases and cancers.
|
30034931 |
2018 |
|
Anemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
The Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project sought to inform the interpretation of iron and vitamin A biomarkers (ferritin, serum transferrin receptor, and retinol binding protein) in settings of prevalent inflammation as well as the prevention of and control strategies to address anemia.
|
28615252 |
2017 |
|
Anemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Relative lack of iron in specific organs/tissues, and IDA in the context of inflammatory disorders, are diagnosed based on arbitrary cut offs of ferritin and transferrin saturation and/or marker combination (as the soluble transferrin receptor/ferritin index) in an appropriate clinical context.
|
28216263 |
2017 |
|
Anemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
These findings strongly suggest that overexpressed TfR1 may play a regulatory role contributing to iron overload and anemia in β-thalassemic mice.
|
28151426 |
2017 |
|
Anemia
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
TfR1 levels in RCC tumors, particularly ccRCC, were significantly associated with adverse clinical prognostic features (anemia, lower body mass index, smoking), worse tumor pathology (size, stage, grade, multifocality, sarcomatoid dedifferentiation) and worse survival outcomes, including after adjustments for tumor pathology.
|
29291011 |
2017 |
|
Anemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Iron deficiency prevalence (inflammation-corrected ferritin <15 μg/L or soluble transferrin receptor >8.3 mg/L) was 67%; anemia was 36%, and vitamin D insufficiency (25(OH)D <30 ng/mL) was 77%.
|
28700535 |
2017 |
|
Anemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Despite the critical role of TfR1 in erythrocyte development and function, patients had only mild anemia and only slightly increased TfR1 expression in erythroid precursors.
|
26642240 |
2016 |
|
Anemia
|
0.200 |
AlteredExpression
|
disease |
LHGDN |
The study showed that the expression of TfR1 mRNA increased significantly (almost three-fold) in the mild anemia group and decreased near to the normal level in the moderate anemia group.
|
18586377 |
2008 |
|
Anemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Duodenal expression of a putative stimulator of Fe transport and transferrin receptor in anemia and hemochromatosis.
|
11313310 |
2001 |
|
Anemia
|
0.200 |
Biomarker
|
disease |
BEFREE |
Soluble transferrin receptor as a potential determinant of iron loading in congenital anaemias due to ineffective erythropoiesis.
|
10468869 |
1999 |
|
Anemia
|
0.200 |
Biomarker
|
disease |
HPO |
|
|
|