|
Hemochromatosis
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Iron was measured in tissues and blood from groups of animals 7 weeks after weaning in three different mouse models expressing a transgene in epidermis: a hyperproliferation model in which the HPV16 E7 gene causes a 3-fold increase in epidermal turnover; an epidermal iron sink model in which overexpression of the transferrin receptor causes a 3-4 fold increase of iron in epidermis; a systemic hemochromatosis knockout model that has been crossed with the epidermal iron sink model.
|
22575277 |
2012 |
|
Hemochromatosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Immunohistochemistry (IHC) of white matter for ceruloplasmin (Cp), haemochromatosis (HFE) and transferrin receptor (TfR) was done.
|
21979376 |
2011 |
|
Hemochromatosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
The gene of haemochromatosis (HFE) encodes the HFE protein which interacts with the transferrin receptor (TFR), lowering its affinity for iron-bound transferrin (TF).
|
21384276 |
2011 |
|
Hemochromatosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
An unusual case of hemochromatosis due to a new compound heterozygosity in HFE (p.[Gly43Asp;His63Asp]+[Cys282Tyr]): structural implications with respect to binding with transferrin receptor 1.
|
18157833 |
2008 |
|
Hemochromatosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
To understand the role of hemochromatosis and transferrin receptor system mutations in breast cancer, we analyzed 19 sequence variations at HFE, TFR1, TFR2, and FPN1 and compared genotype frequencies between cases and controls in a German population.
|
15894659 |
2005 |
|
Hemochromatosis
|
0.100 |
Biomarker
|
disease |
LHGDN |
Transferrin receptor co-localizes and interacts with the hemochromatosis factor (HFE) and the divalent metal transporter-1 (DMT1) in trophoblast cells.
|
15880641 |
2005 |
|
Hemochromatosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Soluble transferrin receptor and mutations in hemochromatosis and transferrin genes in a general Catalan population.
|
15698609 |
2005 |
|
Hemochromatosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
The soluble transferrin receptor as a marker of iron homeostasis in normal subjects and in HFE-related hemochromatosis.
|
15642666 |
2005 |
|
Hemochromatosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Hemochromatosis and transferrin receptor gene polymorphisms in chronic hepatitis C: impact on iron status, liver injury and HCV genotype.
|
14557859 |
2003 |
|
Hemochromatosis
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
A study of genes that may modulate the expression of hereditary hemochromatosis: transferrin receptor-1, ferroportin, ceruloplasmin, ferritin light and heavy chains, iron regulatory proteins (IRP)-1 and -2, and hepcidin.
|
11783942 |
2003 |
|
Hemochromatosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Duodenal expression of a putative stimulator of Fe transport and transferrin receptor in anemia and hemochromatosis.
|
11313310 |
2001 |
|
Hemochromatosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Interaction between haemochromatosis and transferrin receptor genes in hepatocellular carcinoma.
|
11096344 |
2000 |
|
Hemochromatosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
TfR2 has a pattern of expression and regulation that is distinct from TfR, and mutations in TfR2 have been recognized as the cause of a non-HFE linked form of hemochromatosis (Camaschella, C., Roetto, A., Cali, A., De Gobbi, M., Garozzo, G., Carella, M., Majorano, N., Totaro, A., and Gasparini, P. (2000) Nat.Genet.25, 14-15).
|
11027676 |
2000 |
|
Hemochromatosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Interaction between haemochromatosis and transferrin receptor genes in different neoplastic disorders.
|
10383894 |
1999 |
|
Hemochromatosis
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Hepatic transferrin, transferrin receptor and ferritin protein expression was localized predominantly to hepatocytes and was increased in patients with genetic haemochromatosis when compared with normal controls.
|
9715407 |
1998 |
|
Hemochromatosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
It was concluded that there is no evidence of generalized dysregulation of the transferrin receptor in hemochromatosis or African siderosis.
|
8178799 |
1994 |
|
Hemochromatosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
We have looked for genes for ferritin and its translational control protein that could account for anomalies in the expression of ferritin (FT) and the transferrin receptor in the duodenum of individuals with hemochromatosis (HC).
|
8045562 |
1994 |