|
Malaria
|
0.090 |
Biomarker
|
disease |
BEFREE |
Arenaviruses and the malaria parasite exploit CD71 for cell invasion and epitopes on CD71 for interaction with transferrin and pathogenic hosts were identified.
|
30850661 |
2019 |
|
Malaria
|
0.090 |
Biomarker
|
disease |
BEFREE |
A blood sample was collected at the first antenatal visit to diagnose malaria and measure serum ferritin (SF), soluble transferrin receptor, C-reactive protein, and α1-acid-glycoprotein.Malaria prevalence was 7.5%.
|
29313480 |
2018 |
|
Malaria
|
0.090 |
Biomarker
|
disease |
BEFREE |
We measured iron biomarkers (ferritin, soluble transferrin receptor [sTfR], hepcidin) and red cell indices (hemoglobin, mean corpuscular volume [MCV]) in newly diagnosed, antiretroviral therapy-naive, HIV-infected (<i>N</i> = 138) and uninfected (<i>N</i> = 52) Kenyan adults enrolled in a study of the immune response to malaria.
|
29943722 |
2018 |
|
Malaria
|
0.090 |
Biomarker
|
disease |
BEFREE |
Malaria exacerbates inflammation-associated elevation in ferritin and soluble transferrin receptor with only modest effects on iron deficiency and iron deficiency anaemia among rural Zambian children.
|
29121448 |
2018 |
|
Malaria
|
0.090 |
Biomarker
|
disease |
BEFREE |
Soluble transferrin receptor concentration was higher in the presence of inflammation and/or malaria.
|
29016317 |
2017 |
|
Malaria
|
0.090 |
Biomarker
|
disease |
BEFREE |
The relative increase in malaria risk for children with high iron status was statistically significant only among those with a concurrently normal serum soluble transferrin receptor concentration (<8.3 mg/L; IRR: 1.97; 95% CI: 1.20, 7.37).<b>Conclusions:</b> Iron adequacy in 4- to 8-y-old children in rural Zambia was associated with increased malaria risk.
|
28701387 |
2017 |
|
Malaria
|
0.090 |
Biomarker
|
disease |
BEFREE |
Elevated soluble transferrin receptor concentration (>8.3 mg/L) was associated with younger age, malaria, greater mean reticulocyte counts, inflammation, HbSS genotype, and ID.
|
28671630 |
2017 |
|
Malaria
|
0.090 |
Biomarker
|
disease |
BEFREE |
Together, these results indicate that TFR1 deficiency alters erythrocyte physiology in a way that is similar to dietary iron deficiency anemia, albeit to a lesser degree, and that this promotes intraerythrocytic parasite survival and an increased susceptibility to malaria in mice.
|
26303393 |
2015 |
|
Malaria
|
0.090 |
Biomarker
|
disease |
BEFREE |
Samples were taken to assess haemoglobin (Hb) concentration, iron status (ferritin, zinc protoporphyrin, transferrin saturation, and soluble transferrin receptor concentration), haptoglobin concentration, alpha-1-antichymotrypsin (a measure of inflammation), and malaria parasites on blood film.
|
16637741 |
2006 |