Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Tumor staging, either postoperatively or by imaging, and measuring the tumor markers thyroglobulin for DTC and calcitonin for MTC, allow for dynamic risk-adapted stratification for follow-up procedures. 27742787 2016
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Routine thyroglobulin, neck ultrasound and physical examination in the routine follow up of patients with differentiated thyroid cancer-Where is the evidence? 30128957 2018
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE We report an innovative fiber optic nano-optrode based on Long Period Gratings (LPGs) working in reflection mode for the detection of human Thyroglobulin (TG), a protein marker of differentiated thyroid cancer. 26896794 2016
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Moreover, TgAb in different concentrations had an effect on the diagnosis of metastasis of differentiated thyroid cancer via Tg. 29442477 2019
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Low or Undetectable Basal Thyroglobulin Levels Obviate the Need for Neck Ultrasound in Differentiated Thyroid Cancer Patients After Total Thyroidectomy and <sup>131</sup>I Ablation. 29665748 2018
Primary differentiated carcinoma of thyroid gland
0.100 AlteredExpression disease BEFREE The aim of our study was to verify the diagnostic accuracy of <sup>131</sup>I-pT-WBS and SPECT/CT imaging (post-therapeutic imaging) compared to serum Tg levels in detecting metastases in early stage of DTC patients. 29707123 2018
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Thyroglobulin autoantibodies before radioiodine ablation predict differentiated thyroid cancer outcome. 28467308 2017
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE A highly sensitive thyroglobulin assay (Elecsys® Tg II, Roche Diagnostics, Penzberg, Germany) has become available for monitoring patients with differentiated thyroid cancer (DTC). 28960391 2018
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Serum thyroglobulin monitoring along with anatomic and functional imaging play key roles in the surveillance of patients with differentiated thyroid cancer after initial treatment. 30717906 2019
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Surveillance of patients with differentiated thyroid cancer and indeterminate response: a longitudinal study on basal thyroglobulin trend. 30963467 2019
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE In this study, we aimed to assess the association between ablative stimulated Tg obtained before radioactive iodine ablation therapy (RAI) (ASTg) and late stimulated Tg obtained 6-12 months after primary therapy (LSTg) in a group of subjects with DTC. 28258491 2017
Primary differentiated carcinoma of thyroid gland
0.100 AlteredExpression disease BEFREE These techniques were used to model the relationship between thyroglobulin levels in individuals with differentiated thyroid cancer before and after treatment with radioactive iodine (I-131). 29557257 2019
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Assessing the utility of preoperative serum thyroglobulin in differentiated thyroid cancer: a retrospective cohort study. 29948933 2018
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Changing Trend of Thyroglobulin Antibodies in Patients With Differentiated Thyroid Cancer Treated With Total Thyroidectomy Without <sup>131</sup>I Ablation. 29860933 2018
Primary differentiated carcinoma of thyroid gland
0.100 AlteredExpression disease BEFREE Prognostic Value of Stimulated Thyroglobulin Levels at the Time of Radioiodine Administration in Differentiated Thyroid Cancer. 30283740 2018
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Our findings suggest that rosiglitazone treatment may induce radioiodine uptake in some patients with thyroglobulin-positive and radioiodine-negative differentiated thyroid cancer. 17188145 2006
Primary differentiated carcinoma of thyroid gland
0.100 AlteredExpression disease BEFREE Thyroglobulin levels measured at the time of remnant ablation to predict response to treatment in differentiated thyroid cancer after thyroid hormone withdrawal or recombinant human TSH. 27655291 2017
Primary differentiated carcinoma of thyroid gland
0.100 AlteredExpression disease BEFREE Low specificity of blood thyroglobulin messenger ribonucleic acid assay prevents its use in the follow-up of differentiated thyroid cancer patients. 14715824 2004
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Although the measurement of thyroglobulin mRNA from peripheral blood is likely to affect the future management of these patients, it is expected that serum thyroglobulin measurement will continue to have a principal role in the care of patients with differentiated thyroid cancer. 11444170 2001
Primary differentiated carcinoma of thyroid gland
0.100 AlteredExpression disease BEFREE A higher elevation of Tg levels after RAI may be associated with a better treatment outcome in DTC patients with distant metastasis. 30382500 2019
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Fourteen patients with DTC (21%) had Tg antibodies, three with local disease (all positive for TSHR-mRNA), and 11 with no evidence of disease (all negative for TSHR-mRNA). 15292293 2004
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE The study population (Group A) included all patients with low-risk differentiated thyroid cancer (DTC) who underwent total thyroidectomy and RAI between 1/1/2006 to 9/11/2015 with intrathyroidal T1-T2, Nx, N0 or N1a (≤5 nodes all measuring, when reported, <2 mm) that had anti-thyroglobulin antibodies. 28510122 2017
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE This is an institutional review board-approved retrospective study of patients who underwent lymph node fine needle aspiration biopsy with thyroglobulin washout between 2012 and 2018, during the post-total thyroidectomy follow-up of differentiated thyroid cancer. 31495510 2020
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Evaluation of the ability of stimulated thyroglobulin (Tg) and Tg reduction index (TRI) to predict long-term remission in patients with DTC managed by thyroidectomy and radioactive iodine (RAI) remnant ablation. 30785995 2019
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE <b>Background:</b> In patients with differentiated thyroid cancer (DTC) and raising serum thyroglobulin (Tg) after total or near-total thyroidectomy and <sup>131</sup>I remnant ablation an empiric <sup>131</sup>I therapy may be considered. 30930852 2019