Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE <b>Background:</b> In patients with differentiated thyroid cancer (DTC) and raising serum thyroglobulin (Tg) after total or near-total thyroidectomy and <sup>131</sup>I remnant ablation an empiric <sup>131</sup>I therapy may be considered. 30930852 2019
Primary differentiated carcinoma of thyroid gland
0.100 AlteredExpression disease BEFREE <sup>99m</sup>Tc-sestamibi may have a role in thyroid cancer localization when physical exam, neck ultrasound, radioiodine scan, chest/abdomen CT, and <sup>18</sup>F-FDG PET/CT does not identify the source of elevated Tg levels in DTC. 29797211 2018
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Differentiated thyroid cancer (DTC) patients with negative serum thyroglobulin (Tg), negative <sup>131</sup>I whole-body scintigraphy (<sup>131</sup>I-WBS) at first post-ablation and progressively increased TgAb level are a relatively rare entity in the follow-up after total thyroidectomy and radioactive iodine therapy. 28588229 2017
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Differentiated thyroid cancer (DTC) with thyroglobulin elevation and negative I scintigraphy (TENIS) syndrome is a diagnostic and therapeutic dilemma. 30080688 2018
Primary differentiated carcinoma of thyroid gland
0.100 AlteredExpression disease BEFREE Thyroglobulin levels measured at the time of remnant ablation to predict response to treatment in differentiated thyroid cancer after thyroid hormone withdrawal or recombinant human TSH. 27655291 2017
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Thyroglobulin autoantibodies before radioiodine ablation predict differentiated thyroid cancer outcome. 28467308 2017
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Thyroglobulin measurement in the management of patients with differentiated thyroid cancer. 29546779 2018
Primary differentiated carcinoma of thyroid gland
0.100 AlteredExpression disease BEFREE A higher elevation of Tg levels after RAI may be associated with a better treatment outcome in DTC patients with distant metastasis. 30382500 2019
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE A highly sensitive thyroglobulin assay (Elecsys® Tg II, Roche Diagnostics, Penzberg, Germany) has become available for monitoring patients with differentiated thyroid cancer (DTC). 28960391 2018
Primary differentiated carcinoma of thyroid gland
0.100 AlteredExpression disease BEFREE A methodological standardization that can distinguish specific from non-specific TG mRNA amplification might be of great interest for the follow-up of differentiated thyroid cancer, especially in patients with high levels of anti-TG antibodies. 19169488 2008
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Along with the detection of serum thyroglobulin and anatomic imaging modalities, such as ultrasound and computer tomography, radionuclide molecular imaging plays a vital role in the evaluation of RR-DTC. 29650270 2018
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Although the measurement of thyroglobulin mRNA from peripheral blood is likely to affect the future management of these patients, it is expected that serum thyroglobulin measurement will continue to have a principal role in the care of patients with differentiated thyroid cancer. 11444170 2001
Primary differentiated carcinoma of thyroid gland
0.100 AlteredExpression disease BEFREE As recurrences after treatment for differentiated thyroid cancer can occur many years after thyroidectomy, periodic monitoring of serum thyroglobulin (Tg) levels is performed in these patients. 12542917 2003
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Assessing the utility of preoperative serum thyroglobulin in differentiated thyroid cancer: a retrospective cohort study. 29948933 2018
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Changing Trend of Thyroglobulin Antibodies in Patients With Differentiated Thyroid Cancer Treated With Total Thyroidectomy Without <sup>131</sup>I Ablation. 29860933 2018
Primary differentiated carcinoma of thyroid gland
0.100 AlteredExpression disease BEFREE Clinical utility of an ultrasensitive thyroglobulin assay in the follow-up of patients with differentiated thyroid cancer: can the stimulation test be avoided in patients with an intermediate recurrence risk? 29984794 2018
Primary differentiated carcinoma of thyroid gland
0.100 GeneticVariation disease BEFREE Common variants of the thyroglobulin gene are associated with differentiated thyroid cancer risk. 21476894 2011
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Comparison of day 3 and day 5 thyroglobulin results after thyrogen injection in differentiated thyroid cancer patients. 29854387 2018
Primary differentiated carcinoma of thyroid gland
0.100 AlteredExpression disease BEFREE Currently, the most valuable role FDG-PET/CT exists in the work-up of patients with differentiated thyroid cancer status post thyroidectomy who present with increasing thyroglobulin levels and a negative (131)I whole-body scan. 21272686 2011
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Detection of distant metastasis at the time of ablation in children with differentiated thyroid cancer: the value of pre-ablation stimulated thyroglobulin. 29953410 2018
Primary differentiated carcinoma of thyroid gland
0.100 AlteredExpression disease BEFREE Evaluation of quantitative measurement of thyroglobulin mRNA in the follow-up of differentiated thyroid cancer. 14588101 2003
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Evaluation of the ability of stimulated thyroglobulin (Tg) and Tg reduction index (TRI) to predict long-term remission in patients with DTC managed by thyroidectomy and radioactive iodine (RAI) remnant ablation. 30785995 2019
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Follow-up of patients with thyroglobulin-antibodies: Rising Tg-Ab trend is a risk factor for recurrence of differentiated thyroid cancer. 28509618 2017
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Follow-up of patients with low-risk differentiated thyroid cancer treated with total thyroidectomy and radioiodine requires neck sonography and thyroglobulin (Tg). 28543974 2017
Primary differentiated carcinoma of thyroid gland
0.100 Biomarker disease BEFREE Fourteen patients with DTC (21%) had Tg antibodies, three with local disease (all positive for TSHR-mRNA), and 11 with no evidence of disease (all negative for TSHR-mRNA). 15292293 2004