TGFB1, transforming growth factor beta 1, 7040

N. diseases: 1558; N. variants: 50
Disease: Cataract ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0086543
Disease: Cataract
Cataract 		0.050 AlteredExpression disease BEFREE The expression of PAI-1 mRNA and TGF-β1 mRNA was significantly higher in the cDNA samples obtained from the atopic cataracts than those obtained from the senile cataracts. 22410565 2012
CUI: C0086543
Disease: Cataract
Cataract 		0.050 AlteredExpression disease BEFREE Significant differences were found for TGFβ1 and TGFβ2 expression profiles in PBMCs between the patients with congenital and traumatic cataracts. 22128246 2011
CUI: C0086543
Disease: Cataract
Cataract 		0.050 Biomarker disease BEFREE TGFbeta is a potent candidate for epithelial-mesenchymal transition (EMT) during the development of anterior polar cataracts in the human lens. 17525203 2007
CUI: C0086543
Disease: Cataract
Cataract 		0.050 Biomarker disease BEFREE Rat lens explants treated with TGF-beta1 or H2O2 developed a cataract similar to human ASC or WC, respectively, which resulted in a markedly decreased expression of 1-cysPrx mRNA and protein. 16360653 2006
CUI: C0086543
Disease: Cataract
Cataract 		0.050 AlteredExpression disease BEFREE Expression of mRNAs for TGF-beta1, TGF-beta2, TGF-beta receptor type II, and connective tissue growth factor (CTGF) was significantly greater in anterior polar type than in nuclear type cataracts. 10440257 1999