Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Conventional (Clear Cell) Renal Cell Carcinoma
0.030 Biomarker disease BEFREE We demonstrate that miR-17 overexpression interferes with the TGFβ-EMT axis and hinders RCC sphere formation; and validated TGFBR2 as a direct and biologically relevant target during this process. 25011053 2015
Conventional (Clear Cell) Renal Cell Carcinoma
0.030 AlteredExpression disease BEFREE Our results suggest that the low TbetaR-II protein level is due to augmented ubiquitin-dependent degradation via Smurf2 and might be involved in the attenuation of TGF-beta signaling pathway in RCC. 20073064 2010
Conventional (Clear Cell) Renal Cell Carcinoma
0.030 AlteredExpression disease BEFREE These results suggest that a loss of TbetaR-II expression in the primary tumor is a significant prognostic factor in patients with RCC. 12736050 2003