TGM2, transglutaminase 2, 7052

N. diseases: 315; N. variants: 14
Disease: Hypertensive disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.330 Biomarker group BEFREE Our data indicate an essential and systemic role for TG2 in bridging inflammation to hypertension via its posttranslational modifications stabilizing AT1 receptor and sensitizing Ang II. 30715101 2019
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.330 Biomarker group BEFREE (ii) Another mechanism by which TG2 may contribute to hypertension is by PTM of AT1Rs at glutamine 315. 28338973 2017
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.330 Biomarker group BEFREE Transglutaminase 2 in pulmonary and cardiac tissue remodeling in experimental pulmonary hypertension. 28775095 2017
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.330 Biomarker group CTD_human Small artery remodeling and erythrocyte deformability in L-NAME-induced hypertension: role of transglutaminases. 17898543 2008