TGM2, transglutaminase 2, 7052

N. diseases: 315; N. variants: 14
Disease: insulinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021670
Disease: insulinoma
insulinoma 		0.030 AlteredExpression disease BEFREE Endoplasmic reticulum (ER) stress in insulinoma cells increased cytosolic calcium and the activity of tissue transglutaminase 2 (tTG2). 29654212 2018
CUI: C0021670
Disease: insulinoma
insulinoma 		0.030 AlteredExpression disease BEFREE Finally, exposure of non-antigenic murine insulinomas to chemical ER stress in vitro or physiological ER stress in vivo caused increased ER stress and Tgase2 activity, culminating in higher BDC2.5 responses. 27173406 2016
CUI: C0021670
Disease: insulinoma
insulinoma 		0.030 Biomarker disease BEFREE At 6-month reviews, length (or height) and weight, antibodies to insulin, GAD65, the tyrosine phosphatase-like insulinoma antigen, and tissue transglutaminase were measured. 18835948 2009