THBS1, thrombospondin 1, 7057

N. diseases: 480; N. variants: 10
Disease: Diabetic Angiopathies ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011875
Disease: Diabetic Angiopathies
Diabetic Angiopathies 		0.320 Biomarker disease BEFREE These results suggest that therapeutic TSP-1 inhibition may have important atheroprotective potential in diabetic vascular disease. 28345659 2017
CUI: C0011875
Disease: Diabetic Angiopathies
Diabetic Angiopathies 		0.320 Biomarker disease CTD_human Upregulation of CREM/ICER suppresses wound endothelial CRE-HIF-1α-VEGF-dependent signaling and impairs angiogenesis in type 2 diabetes. 25381014 2015
CUI: C0011875
Disease: Diabetic Angiopathies
Diabetic Angiopathies 		0.320 Biomarker disease BEFREE A putative binding site for the transcription factor aryl hydrocarbon receptor (AhR) was identified in the glucose-responsive fragment of the promoter of thrombospondin-1, a potent antiangiogenic and proatherogenic protein involved in development of diabetic vascular complications. 18515748 2008