THBS2, thrombospondin 2, 7058

N. diseases: 149; N. variants: 13
Disease: Congestive heart failure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.030 GeneticVariation disease BEFREE Two proteins, angiopoietin-2 and thrombospondin-2, were associated with HF in 3 separate validation cohorts. 31047008 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.030 Biomarker disease BEFREE It has been shown in recent studies that TSP-2 is a useful predictor of cardiovascular death in patients with heart failure (HF). 30745537 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.030 Biomarker disease BEFREE Angiotensin II induced fatal cardiac rupture in 70% of TSP2 knockout mice, with cardiac failure in the surviving mice; this was not seen in wild-type mice. 15284191 2004