TIMP3, TIMP metallopeptidase inhibitor 3, 7078

N. diseases: 325; N. variants: 19
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.040 Biomarker disease BEFREE MicroRNA-181b Controls Atherosclerosis and Aneurysms Through Regulation of TIMP-3 and Elastin. 27756793 2017
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.040 AlteredExpression disease BEFREE Furthermore, silencing miR-712 by anti-miR-712 rescues TIMP3 expression and prevents atherosclerosis in murine models of atherosclerosis. 24346612 2013
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.040 AlteredExpression disease BEFREE Systemic insulin resistance and subclinical atherosclerosis are associated with decreased IRS2 and TIMP3 expression in circulating monocytes. 21984580 2011
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.040 GeneticVariation disease BEFREE We tested its association with atherosclerosis in subjects with type 2 diabetes and identified Sirtuin 1 (SirT1) as a major regulator of TIMP3 expression. 19581416 2009