TLR2, toll like receptor 2, 7097

N. diseases: 749; N. variants: 15
Disease: Eclampsia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0013537
Disease: Eclampsia
Eclampsia 		0.010 GeneticVariation disease BEFREE While the TLR-2 +2258 (G>A) and MMP-9 -1562 (C>T) SNPs failed to present any significant association with pre-eclampsia, there was a marked trend for an association between the IL-4 -590 (C>T) SNP and pre-eclampsia (chi(2)= 5.87, P = 0.055), with a prevalence of TT homozygous women in this group (OR 4.455, 95% CI 1.286-15.350). 18651887 2008