TLR2, toll like receptor 2, 7097

N. diseases: 749; N. variants: 15
Disease: Meningitis, Listeria ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025293
Disease: Meningitis, Listeria
Meningitis, Listeria 		0.010 Biomarker disease BEFREE Animal studies have shown that TLR2-knockout mice are more susceptible to septicemia due to Staphylococcus aureus and Listeria monocytogenes, meningitis due to Streptococcus pneumoniae, and infection with Mycobacterium tuberculosis, suggesting that functional TLR2 polymorphisms may impair host response to a certain spectrum of microbial pathogens. 16237639 2005