TLR4, toll like receptor 4, 7099

N. diseases: 1174; N. variants: 54
Disease: Diabetes ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011847
Disease: Diabetes
Diabetes 		0.100 Biomarker disease BEFREE In obesity, the amplified TLR4 response may potentiate β-cell damage and accelerate diabetes progression. 30287405 2019
CUI: C0011847
Disease: Diabetes
Diabetes 		0.100 Biomarker disease BEFREE The Toll-like receptor 4 (TLR4) regulates inflammatory responses in several pathological conditions including diabetes and OA. 30953645 2019
CUI: C0011847
Disease: Diabetes
Diabetes 		0.100 Biomarker disease BEFREE To investigate whether pharmacological blockade of TLR4 affects erectile function in a murine model of diabetes. 30145096 2018
CUI: C0011847
Disease: Diabetes
Diabetes 		0.100 Biomarker disease BEFREE In conclusion, UA alleviates inflammation and inhibits diabetes‑induced nephropathy through a TLR4‑mediated inflammatory pathway. 30221655 2018
CUI: C0011847
Disease: Diabetes
Diabetes 		0.100 GeneticVariation disease BEFREE We evaluated whether the Asp299Gly polymorphism in the TLR4 gene, which impairs inflammatory responses, is associated with reduced vascular inflammation (assessed by C-reactive protein [CRP]) and a decreased risk for CAD and diabetes. 15632890 2004