Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Painful (mechanical and thermal hypersensitivity, ongoing pain and arthritis score) and inflammatory (oedema, plasma extravasation, cell infiltration and IL-1β release) parameters were assessed several hours after intra-articular injection of MSU (100 µg/articulation) in wild-type or knockout mice for Toll-like receptor 4 (TLR4), inducible nitric oxide synthase (iNOS), transient receptor potential (TRP) V1 and the IL-1 receptor (IL-1R).
|
31298290 |
2020 |
Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Levetiracetam mitigates lipopolysaccharide-induced JAK2/STAT3 and TLR4/MAPK signaling pathways activation in a rat model of adjuvant- induced arthritis.
|
29501867 |
2018 |
Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
The severity of arthritis was assessed clinically, biochemically, and histologically.Immunostaining for TLR4 was performed.
|
27271273 |
2018 |
Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
We further identify a role for TLR4 activation in the intestinal lamina propria production of IL-17 and cytokines involved in Th17 differentiation preceding the onset of arthritis.
|
28645307 |
2017 |
Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Effect of Scutellarin inhibits collagen‑induced arthritis through TLR4/NF‑κB‑mediated inflammation.
|
28849116 |
2017 |
Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Pathogenic roles of CXCL10 signaling through CXCR3 and TLR4 in macrophages and T cells: relevance for arthritis.
|
28724396 |
2017 |
Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
We are thus evaluating the properties of ESP-B4 on LPS-induced THP-1 pro-monocytic cells and adjuvant-induced arthritis in Wistar rats via TLR4.
|
26835987 |
2016 |
Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
In the Polish population of SLE patients, 1196C/T polymorphism of TLR4 gene does not increase the risk of development of NPSLE; however, genotype CC and a dominant allele C is associated with arthritis in the course of SLE.
|
24243911 |
2013 |
Arthritis
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
As chemerin enhanced expression of TLR4 and induced release of CCL2 in SFs, a role of this protein in innate immune system-associated joint inflammation is proposed.
|
22037282 |
2012 |
Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
The study further supports the role of TLR4 in the propagation of joint inflammation and destruction.
|
21858160 |
2011 |
Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
The haplotype of TLR4 may increase the risk for developing BD and the complication of arthritis in the Korean population.
|
19395541 |
2009 |
Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
We investigated the involvement of TLR2, TLR4, and TLR9 in the progression of arthritis using IL-1 receptor antagonist-knockout (IL1rn-/-) mice, which spontaneously develop an autoimmune T cell-mediated arthritis.
|
18060042 |
2008 |
Arthritis
|
0.200 |
Biomarker
|
disease |
LHGDN |
Neither TLR-2 expression nor TLR-4 expression differed between RA and other forms of inflammatory arthritis.
|
17599732 |
2007 |
Arthritis
|
0.200 |
AlteredExpression
|
disease |
BEFREE |
Neither TLR-2 expression nor TLR-4 expression differed between RA and other forms of inflammatory arthritis.
|
17599732 |
2007 |
Arthritis
|
0.200 |
Biomarker
|
disease |
HPO |
|
|
|