TLR4, toll like receptor 4, 7099

N. diseases: 1174; N. variants: 54
Disease: Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.320 AlteredExpression group BEFREE TLR4 expression was present in all ovarian epithelium (normal and neoplastic), whereas MyD88 was restricted to neoplastic cells, independent of tumour grade and associated with reduced progression-free and overall survival, in an immunohistological specific subset of serous carcinomas, p<0.05. 24977712 2014
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.320 AlteredExpression group BEFREE However, recent studies have shown that TLR4 is aberrantly expressed in various types of carcinomas and may correlate with tumor progression. 21152870 2011
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.320 Biomarker group CTD_human Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. 22180778 2011