TLR4, toll like receptor 4, 7099

N. diseases: 1174; N. variants: 54
Disease: Eosinophilia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014457
Disease: Eosinophilia
Eosinophilia 		0.320 Biomarker disease BEFREE Augmented TLR4 driven eosinophilia and greater TNF-α responses observed in AMP-LPS treated mice independent of TLR-4 expression, suggests activation of allergic responses by TLR4 and non-TLR4 pathways larger than those induced by LPS administered alone. 29357863 2018
CUI: C0014457
Disease: Eosinophilia
Eosinophilia 		0.320 Biomarker disease CTD_human Desert dust induces TLR signaling to trigger Th2-dominant lung allergic inflammation via a MyD88-dependent signaling pathway. 26882889 2016
CUI: C0014457
Disease: Eosinophilia
Eosinophilia 		0.320 Biomarker disease BEFREE TLR4-deficient mice challenged with either OVA preparation showed eosinophilia but not neutrophilia and had increased IL-5. 24968337 2014