TLR4, toll like receptor 4, 7099

N. diseases: 1174; N. variants: 54
Disease: polyps ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032584
Disease: polyps
polyps 		0.010 Biomarker phenotype BEFREE In this study, Apc<sup>Min/+</sup> intestinal adenoma mice were generated on TLR4-sufficient and TLR4-deficient backgrounds to investigate the carcinogenic effect of TLR4 in mouse gut by comparing mice survival, peripheral blood cells, bone marrow haematopoietic precursor cells and numbers of polyps in the guts of Apc<sup>Min/+</sup> WT and Apc<sup>Min/+</sup> TLR4<sup>-/-</sup> mice. 31650683 2020