TLR4, toll like receptor 4, 7099

N. diseases: 1174; N. variants: 54
Disease: Acute anterior uveitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0701807
Disease: Acute anterior uveitis
Acute anterior uveitis 		0.030 Biomarker disease BEFREE Increased expression of miRNA146a (p<0.01), miRNA155 (p<0.05) and miRNA125a5p (p<0.01) was demonstrated in AU PBMC compared with HC. miRNA155 was increased following TLR1/2 (p<0.05) and TLR4 (p<0.05) stimulation and miRNA146a increased in response to IL1β (p<0.05). 30297336 2019
CUI: C0701807
Disease: Acute anterior uveitis
Acute anterior uveitis 		0.030 GeneticVariation disease BEFREE The purpose of this study was to investigate the role of TLR2 and TLR4 gene polymorphisms in the pathogenesis of AAU. 22128242 2011
CUI: C0701807
Disease: Acute anterior uveitis
Acute anterior uveitis 		0.030 Biomarker disease BEFREE IL-6 and IFN-gamma production stimulated by TLR4 activation was significantly reduced in patients with AAU, compared with that in healthy control subjects (P < 0.05). 17389503 2007