TLR4, toll like receptor 4, 7099

N. diseases: 1174; N. variants: 54
Disease: Acute Chest Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.070 AlteredExpression disease BEFREE We found that mRNA expression levels of TLR2 but not TLR 4 and 9 are up-regulated in platelets of patients with ACS when compared to patients without coronary atherosclerosis. 31644579 2019
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.070 Biomarker disease BEFREE TLR4, miR-155, and inflammatory cytokines may be closely related to ACS. 28407320 2018
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.070 Biomarker disease BEFREE S100A8/A9 expression was significantly correlated with TLR-4 and COX-2 in the ACS group and with TLR-4 in the CHD group. 30367682 2018
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.070 Biomarker disease BEFREE TLR-4 might play a more important role than TLR-2 in atherogenesis, especially in ACS. 25179298 2016
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.070 Biomarker disease BEFREE Pharmacologic inhibition of TLR4 and hemopexin replacement therapy prior to hemin infusion protected sickle mice from developing ACS. 24084741 2013
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.070 AlteredExpression disease BEFREE The TLR4 expression levels were significantly higher in the ACS group than in the SAP group. 19556696 2009
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.070 AlteredExpression disease BEFREE We suggest that TLR4 and MAPK families maybe involved in activation of circulating DC of ACS patients. 18373609 2008