TLR4, toll like receptor 4, 7099

N. diseases: 1174; N. variants: 54
Disease: Diabetic Neuralgia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0751074
Disease: Diabetic Neuralgia
Diabetic Neuralgia 		0.310 Biomarker disease BEFREE High glucose-induced oxidative stress and inflammatory responses play an important role in painful diabetic neuropathy by activating the TLR4/NFκB signal pathway. 29719281 2018
CUI: C0751074
Disease: Diabetic Neuralgia
Diabetic Neuralgia 		0.310 Biomarker disease CTD_human Asp299Gly and Thr399Ile genotypes of the TLR4 gene are associated with a reduced prevalence of diabetic neuropathy in patients with type 2 diabetes. 14693986 2004