SERPING1, serpin family G member 1, 710

N. diseases: 207; N. variants: 43
Disease: Asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004096
Disease: Asthma
Asthma 		0.020 Biomarker disease BEFREE We explored the effect of human plasma-derived C1-INH on allergic lung inflammation in a house dust mite (HDM) induced asthma mouse model by daily administration of C1-INH (15 U) during the challenge phase. 29036225 2017
CUI: C0004096
Disease: Asthma
Asthma 		0.020 Biomarker disease BEFREE HAE1, also known as PRO98498, is structurally similar to omalizumab (Xolair®), a humanized anti-IgE IgG1 marketed for the treatment of asthma, but differs by 9 amino acid changes in the complementarity-determining region resulting in a 23-fold improvement in affinity. 23778267 2014