TLR5, toll like receptor 5, 7100

N. diseases: 163; N. variants: 6
Disease: Chorioamnionitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008495
Disease: Chorioamnionitis
Chorioamnionitis 		0.020 Biomarker phenotype BEFREE The role of TLR5 in chorioamnionitis remains unclear: however, TLR5 was reported to have a significantly stronger effect on the induction of interleukin (IL)-6 when compared with other TLRs in amniotic epithelial cells. 29371755 2018
CUI: C0008495
Disease: Chorioamnionitis
Chorioamnionitis 		0.020 GeneticVariation phenotype BEFREE Only RIPK2 (p = 0.0025) and TLR4 (p = 0.0005) were found to increase progressively with GA. We found significant changes in TLR5 (p = 0.01) with CA, NFKBIA (p = 0.016) with PPROM, NKKBIA (p = 0.003), and NFKB1 (p = 0.009) with CA and PPROM. 27440318 2017