TLR5, toll like receptor 5, 7100

N. diseases: 163; N. variants: 6
Disease: Malignant neoplasm of stomach ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.050 GeneticVariation disease BEFREE In conclusion, our study suggests that alterations of flaA protein, moderate motility in <i>H. pylori</i> and two polymorphisms in TLR5 and TLR9 may favor the onset of AAG and GC, at least in a subset of patients. 31083432 2019
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.050 Biomarker disease BEFREE Evaluation of toll-like receptors as prognostic biomarkers in gastric cancer: high tissue TLR5 predicts a better outcome. 31467388 2019
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.050 GeneticVariation disease BEFREE These findings suggest that genetic variants in TLR5 may modify the role of Helicobacter pylori infection in the process of causing GC. 28404962 2017
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.050 GeneticVariation disease BEFREE These findings suggest that TLR2 c. -196 to -174 ins > del, TLR5 rs5744174 and interaction between rs5744174 and H. pylori infection were associated with the development of GC. 21994405 2011
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.050 Biomarker disease BEFREE These findings suggest that TLR5 may play an important role in tumor progression of gastric cancer via the regulation of cell proliferation. 21455558 2011