TM7SF2, transmembrane 7 superfamily member 2, 7108

N. diseases: 217; N. variants: 0
Disease: Fibrosis, Liver ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.060 Biomarker disease BEFREE ACE2-dependent generation of Ang1-7 may inhibit experimental liver fibrosis. inhibition of Ang1-7 clearance by means of neprilysin blockade has portal hypotensive and natriuretic effects. 31580514 2020
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.060 Biomarker disease BEFREE BML-111 equilibrated ACE-AngII-AT1R and ACE2-Ang-(1-7)-Mas axis to protect hepatic fibrosis in rats. 28822808 2017
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.060 Biomarker disease BEFREE Treatment with Ang-(1-7) inhibited mir-21, NLRP3 inflammasome, and liver fibrosis after bile duct ligation (BDL) or AngII infusion. 27502441 2017
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.060 AlteredExpression disease BEFREE Infusion of Ang-(1-7) alleviated BDL-induced liver fibrosis and inhibited the expression of Col1A1 and the activation of NLRP3 inflammasome in hepatocytes. 27445100 2016
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.060 Biomarker disease BEFREE Conversely, Ang-(1-7) infusion reduces fibrosis and proliferation mainly by suppression of hepatic stellate cell activation; Mas receptor antagonism aggravates liver fibrosis and severe liver steatosis. 25453980 2014
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.060 AlteredExpression disease BEFREE The aim of the present study was to assess plasma levels of Ang-(1-7) in human liver disease and determine its effects in experimental liver fibrosis. 19371232 2009