TMSB4X, thymosin beta 4 X-linked, 7114

N. diseases: 130; N. variants: 0
Disease: Sepsis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis 		0.020 Biomarker disease BEFREE Given that Thymosin Beta 4 inhibits the polymerization of F-actin, it is possible that Thymosin Beta 4 decreases mortality in sepsis via the regulation of actin as well as its other anti-inflammatory properties and should be further pursued as a clinical trial in humans with sepsis. 29508629 2018
CUI: C0243026
Disease: Sepsis
Sepsis 		0.020 Biomarker disease BEFREE Here, we analyzed whether treatment with Tβ4 is able to reduce the pericytes loss in lipopolysaccharides (LPS)-induced sepsis and to improve the hemodynamic function and survival in C57BL/6 mice. 25604254 2015