TMSB4X, thymosin beta 4 X-linked, 7114

N. diseases: 130; N. variants: 0
Disease: Dryness of eye ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0314719
Disease: Dryness of eye
Dryness of eye 		0.020 Biomarker phenotype BEFREE Thymosin beta 4 (Tβ4) has important applications in ocular repair and Phase 3 clinical trials using Tβ4 to treat dry eye and neurotrophic keratopathy are currently ongoing. 30063853 2018
CUI: C0314719
Disease: Dryness of eye
Dryness of eye 		0.020 GeneticVariation phenotype BEFREE This study evaluated the clinical activity of RGN-259 (thymosin β4) in comparison with cyclosporine A (CsA), diquafosol (DQS), and lifitegrast (LFA) in a murine model of dry eye. 30002412 2018