|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to explore the association of a variant, TNF-308 G>A, residing in the TNFa gene with cervical cancer.
|
30387170 |
2019 |
|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Therefore the aim of the study was to investigate the allelic distribution of -308 TNF-alpha gene polymorphism in South African women with cervical cancer compared to control women.
|
16438713 |
2006 |
|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to assess the association of TNF-α/rs1799724 and CXCL12/rs266085 polymorphisms with susceptibility to cervical cancer in Han Chinese population in Shandong Province.
|
26191295 |
2015 |
|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We demonstrated that there is no association between TNF rs1800629 polymorphism and the HPV infection, or cervical cancer with HPV infection.
|
23028877 |
2012 |
|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We found no association between TNF-α-308G>A polymorphism and cervical cancer in overall population.
|
23317256 |
2012 |
|
cervical cancer
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
These data suggest that the genetically acquired ability to produce higher levels of TNF-alpha is present in a minority of women with or without cervical cancer in the Zimbabwean population.
|
12657115 |
2003 |
|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Although our findings support the general hypothesis that host immunogenetic determinants other than class II MHC may be important in the development of cervical cancer, further analysis of the HLA gene cluster comprising the implicated TNFalpha single-nucleotide polymorphisms will be required to determine whether their association is linkage independent.
|
12142377 |
2002 |
|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, these results suggest a potential effect of TNF-α -238 G/A in the reduction of cervical cancer risk in Argentine women, but not TNF-α -308 or IL-10.
|
22592655 |
2012 |
|
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
Re-expression of HPV16 E2 in SiHa (human cervical cancer) cells potentiates NF-κB activation induced by TNF-α concurrently increasing senescence and survival.
|
25572145 |
2015 |
|
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
There might be an association of the TLR2 and TLR4 pathways with the immunological response of TNF-α and TNF-β in cervical cancer.
|
28009429 |
2017 |
|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We have evaluated the association of polymorphism at HLA class II DQB1 and the TNF, LTA, TAP1 and TAP2 genes with cervical cancer risk, using 1306 familial cases and 288 controls.
|
18650831 |
2008 |
|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This study investigated the associations between TNF-α-308G>A, -238G>A, and TNFRII - VNTR-322 and cervical cancer in Tunisian women.
|
25113639 |
2015 |
|
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
Fucoxanthin and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Synergistically Promotes Apoptosis of Human Cervical Cancer Cells by Targeting PI3K/Akt/NF-κB Signaling Pathway.
|
29291370 |
2018 |
|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The Correlation Between TNF-α Promoter Gene Polymorphism and Genetic Susceptibility to Cervical Cancer.
|
29940817 |
2018 |
|
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our findings indicate that the association of TNFA with cervical cancer is different with CIN.
|
11600224 |
2001 |
|
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
We report new associations between several TNF-alpha SNPs and susceptibility to cervical cancer that support the involvement of the TNF- alpha promoter region in development of cervical cancer.
|
15717274 |
2005 |
|
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
Although tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) provides tumor-specific apoptosis in various cancers, including cervical cancer, the sensitivity differs depending on the cell lines.
|
27599897 |
2016 |
|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A comprehensive search was conducted to examine all the eligible studies of TNF-α -308 G>A polymorphism and cervical cancer risk.
|
22146770 |
2012 |
|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
All the case-control studies published from January 1989 to October 2010 on the association between the two polymorphisms of TNFA and cervical cancer risk were identified by searching the electronic literature Medline.
|
21670964 |
2012 |
|
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
Cox multivariate analysis disclosed that carbohydrate antigen 153 (CA153), squamous cell carcinoma antigen (SCC) and tumor necrosis factor-α (TNF-α) are associated with prognosis in cervical cancer.
|
23850705 |
2013 |
|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Therefore, our study aimed to investigate the correlation between the polymorphism of TNF-α-308 gene and susceptibility to cervical cancer.
|
29725439 |
2018 |
|
cervical cancer
|
0.100 |
Biomarker
|
disease |
BEFREE |
TNF-α-induced apoptosis has been confirmed, however, relatively little is known regarding the role of forkhead box class-O 1 (FOXO1) in mediating TNF-α-induced apoptosis in cervical cancer.
|
26214423 |
2015 |
|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This meta-analysis proved that TNF-α -238 and -308 G/A polymorphisms could be used to identity individual with elevated susceptibility to cervical cancer in certain populations.
|
31825934 |
2019 |
|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
It suggests that SNP at -308 (G/A) of TNFalpha promoter may represent an increased risk for HPV infection and development of cervical cancer in Indian women.
|
17452777 |
2007 |
|
cervical cancer
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Our meta-analysis indicates that TNF-α polymorphisms may confer susceptibility to cervical cancer in an ethic-specific fashion.
|
25069725 |
2015 |