|
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
Depression after myocardial infarction: TNF-α-induced alterations of the blood-brain barrier and its putative therapeutic implications.
|
23415700 |
2013 |
|
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
Enzyme-linked immunosorbent assay (ELISA) analysis showed that QLQX significantly reduced the levels of angiotensin II (AngII), brain natriuretic peptides (BNP), creatinine (CRE), cystatin C (CysC), tumor necrosis factor (TNF)-α, interleukin (IL)-6, microalbuminuria (MAU), and neutrophil gelatinase-associated lipocalin (NGAL) in plasma induced by myocardial infarction.
|
30068867 |
2018 |
|
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
The serum levels of cardiac troponin I (cTnI) and tumor necrosis factor-α (TNF-α), and myocardial infarct size were measured.
|
26648172 |
2016 |
|
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
C1q/tumor necrosis factor-related protein-3-engineered mesenchymal stromal cells attenuate cardiac impairment in mice with myocardial infarction.
|
31296837 |
2019 |
|
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
We further evaluated the inflammation, fibrosis of left atria (LA), and related signal pathways by RT-PCR, Western blot, and staining analysis.Compared to the MI group, fisetin treatment improved cardiac function, inhibited macrophage recruitment into the LA and production of IL-1β and TNF-α, and attenuated adverse atrial fibrosis following acute myocardial infarction (AMI).
|
31666455 |
2019 |
|
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
Inflammation is a key factor in atherosclerosis, including endothelial function, plaque stabilization and post infarct remodeling; thus, inhibition of TNF-α may affect the inflammatory burden and plaque vulnerability leading to less cardiovascular events and myocardial infarctions.
|
31059840 |
2019 |
|
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
The purpose of this study was to find out the possible association of modulation in NK cell, TNK cells, T cells, B cells, and tumor necrosis factor alpha (TNF-α) in CAD patients and various forms of myocardial infarction.
|
28414590 |
2017 |
|
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
Compared with control group, the levels of heart rate, left ventricular end-diastolic pressure, TNF-α, and IL-6 were increased in each group of rats with MI (all p < 0.05), while the levels of systolic blood pressure, diastolic blood pressure, mean arterial pressure, left ventricular systolic pressure, and IL-10 were significantly decreased (all p < 0.05).
|
31218464 |
2019 |
|
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
On the other hand, p21, S100A4 and TNF-α increased in the stromal fibroblasts of tissue from old myocardial infarctions.
|
28721450 |
2017 |
|
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
S100A8/A9 promotes MMP-9 expression in the fibroblasts from cardiac rupture after myocardial infarction by inducing macrophages secreting TNFα.
|
29949169 |
2018 |
|
Myocardial Infarction
|
0.600 |
PosttranslationalModification
|
disease |
BEFREE |
Atorvastatin can improve cardiac remodeling after myocardial infarction in rats, which may be associated with its inhibition of p38 phosphorylation and its decrease of TNF-α expression.
|
30116330 |
2018 |
|
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
This study aimed to assess serum irisin level in myocardial infarction (MI) with or without heart failure (HF) and the possible relation between irisin and cardiac markers, tumor necrosis factor-α (TNF-α) and lipid profile.
|
30958967 |
2019 |
|
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The expression of IL-6, TNF-α, and inflammatory related molecules ICAM-1, VCAM-1, MMP-2 and -9, nuclear NF-kB, and iNOS, were elevated in MI-V.
|
30642049 |
2019 |
|
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Serum levels of tumor necrosis factor (TNF) rise with aging and have been correlated with the incidence of myocardial infarction.
|
20421368 |
2010 |
|
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Moreover, S+MI group, but not S alone, showed a significant increase in the expression of connective tissue growth factor (CTGF) and fibrotic proteins fibronectin (FN) and <i>α</i>-smooth muscle actin (SMA), in comparison to controls, in addition to a significant increase in mRNA levels of IL-6 and TNF-<i>α</i> inflammatory markers.
|
29177025 |
2017 |
|
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, pretreated group showed decreased activation of TNF-α, Caspase-3 activity along with reduction in the myocardial infarct size.
|
31630586 |
2019 |
|
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Notably, ACE2 overexpression significantly reduced the MI-induced increase in apoptosis, macrophage infiltration, and HMGB1 and proinflammatory cytokine expression (TNF-α and IL-6).
|
26498282 |
2016 |
|
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Gambogic acid suppressed the activation of interleukin (IL)-6 and tumor necrosis factor-α, and increased IL-10 levels in MI rats.
|
29434760 |
2018 |
|
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Dietary supplementation with flaxseed, ALA or SDG before and after the induction of the MI significantly reduced the incidence of arrhythmias and resulted in significantly smaller infarct size, less left ventricle dilation, and decreased myocardial fibrosis and tumor necrosis factor-α levels compared to the control MI group.
|
31284167 |
2019 |
|
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
HSP70 levels were positively correlated with monocyte TLR4, plasma interleukin-6 and tumor necrosis factor-alpha levels in AMI patients.
|
16714144 |
2006 |
|
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
LHGDN |
Increased TNF-alpha and decreased TGF-beta expression in peripheral blood leukocytes after acute myocardial infarction.
|
16718633 |
2006 |
|
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The expression of TNF-alpha, iNOS, VEGF(164) and VEGF(188) was observed during the whole period after myocardial infarction (on days 1, 4, 11, 28 and 40), whereas VEGF(120) was found only on day 1 and 4.
|
11399901 |
2001 |
|
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The MI group showed higher levels of cardiac TNF-α compared to the MIL and MIT groups.
|
28599197 |
2017 |
|
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
LHGDN |
Elevated TNF-alpha levels are associated with increased MI risk.
|
16243340 |
2006 |
|
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The immunohistochemical staining results showed that IL-6 knockout could lower the MI-induced high expression of TNF-α (p<0.05), and Masson's trichrome staining indicated that IL-6 knockout could also repress the degree of cardiac fibrosis.
|
31364133 |
2019 |