TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Disease: Rheumatoid Nodule ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0035450
Disease: Rheumatoid Nodule
Rheumatoid Nodule 		0.010 AlteredExpression disease BEFREE The cytokine profile within the rheumatoid nodule (i.e., presence of IFNgamma but not IL-2, and prominent expression of IL-1beta and TNFalpha together with IL-12, IL-18, IL-15, and IL-10) is similar to the profile of cytokines in the synovial lesion of rheumatoid arthritis, which is generally accepted as being attributable to a Th1-mediated inflammatory mechanism. 12571841 2003