TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Central nervous system demyelination
0.030 Biomarker disease BEFREE The therapeutic approach to CNS demyelination associated to ankylosing spondylitis is a complex issue due to the contraindication of TNF inhibitors in demyelinating diseases. 31398658 2019
Central nervous system demyelination
0.030 Biomarker disease BEFREE Putative mechanisms of TNF-alpha inhibitor-associated CNS demyelination are described. 31845616 2019
Central nervous system demyelination
0.030 Biomarker disease BEFREE In this paper, we review the published case reports of CNS demyelination associated with anti-TNF-α therapy and present the follow-up of our 4 previously reported patients who developed neurologic symptoms suggestive of CNS demyelination after having received anti-TNF-α treatment. 28337644 2017