TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Disease: Hantavirus infection in conditions classified elsewhere and of unspecified site ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0375024
Disease: Hantavirus infection in conditions classified elsewhere and of unspecified site
Hantavirus infection in conditions classified elsewhere and of unspecified site 		0.020 Biomarker disease BEFREE In our study, genetically determined low production of TNF-alpha was associated with some parameters indicating a more severe clinical course of Puumala Hantavirus infection in humans, possibly by impaired activation of TNF-alpha-dependent antiviral mechanisms, which could in turn result in decreased clearance of Hantavirus. 16987073 2006
CUI: C0375024
Disease: Hantavirus infection in conditions classified elsewhere and of unspecified site
Hantavirus infection in conditions classified elsewhere and of unspecified site 		0.020 GeneticVariation disease BEFREE Human leukocyte antigen-B8-DR3 is a more important risk factor for severe Puumala hantavirus infection than the tumor necrosis factor-alpha(-308) G/A polymorphism. 12198621 2002