TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1504404
Disease: Hippocampal sclerosis
Hippocampal sclerosis
0.030 AlteredExpression disease BEFREE Hence, we studied the levels of multiple inflammatory mediators (IL1β, IL1Ra, IL6, IL10, CCL3, CCL4, TNFα and VEGF) along with transcriptional changes of nine related miRNAs and mRNA levels of downstream effectors of significantly altered cytokines/chemokines in brain tissues obtained from patients with HS (n = 26) and FCD (n = 26). 29162878 2017
CUI: C1504404
Disease: Hippocampal sclerosis
Hippocampal sclerosis
0.030 Biomarker disease BEFREE Our results have clearly suggested that three different death receptor apoptotic systems may be associated with the maintenance and progression of TLE-associated HS: (1) TNF-TNFRSF1A, (2) FASLG-FAS, and (3) TNFSF10-TNFRSF10A/B. 27006531 2016
CUI: C1504404
Disease: Hippocampal sclerosis
Hippocampal sclerosis
0.030 AlteredExpression disease BEFREE We found that TNF expression was dramatically upregulated in TLE(HS) patients (P <0.005). 23634661 2013