TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Disease: Tubulointerstitial fibrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1969372
Disease: Tubulointerstitial fibrosis
Tubulointerstitial fibrosis 		0.030 Biomarker phenotype BEFREE Bortezomib attenuates renal interstitial fibrosis in kidney transplantation via regulating the EMT induced by TNF-α-Smurf1-Akt-mTOR-P70S6K pathway. 31140729 2019
CUI: C1969372
Disease: Tubulointerstitial fibrosis
Tubulointerstitial fibrosis 		0.030 Biomarker phenotype BEFREE Results revealed that hypoxia induced epithelial cells apoptosis, inflammatory factor IL-1β and TNF-α release and tubulointerstitial fibrosis. 28163057 2017
CUI: C1969372
Disease: Tubulointerstitial fibrosis
Tubulointerstitial fibrosis 		0.030 Biomarker phenotype BEFREE LAYN may play roles in the generation of renal interstitial fibrosis in GN via TNF-α-induced EMT. 26410531 2015