TNF, tumor necrosis factor, 7124

N. diseases: 340; N. variants: 9
Disease: Mechanical Allodynia ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.400 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.400 Biomarker phenotype CTD_human CT administration produced a significantly reduction (p<0.05) in the mechanical hyperalgesia induced by CG, TNF-α, PGE2 and DA when compared with control group. 26141506 2015
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.400 Biomarker phenotype CTD_human Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions. 20383154 2010
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.400 Biomarker phenotype CTD_human Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type 2 to generate heat hyperalgesia in a mouse cancer model. 18463260 2008
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.400 Biomarker phenotype CTD_human Tumor necrosis factor alpha enhances the sensitivity of rat trigeminal neurons to capsaicin. 18582539 2008
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.400 Biomarker phenotype CTD_human Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: inhibition of cytokine production-dependent mechanism. 17320857 2007
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.400 Biomarker phenotype CTD_human Mitochondrial electron transport in models of neuropathic and inflammatory pain. 16472913 2006
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.400 Biomarker phenotype CTD_human Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants. 12727271 2003
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.400 Biomarker phenotype CTD_human Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. 10401557 1999
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.400 Biomarker phenotype CTD_human Cytokine-mediated inflammatory hyperalgesia limited by interleukin-10. 7582491 1995
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.400 Biomarker phenotype CTD_human S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance. 7881729 1995