TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Disease: AA amyloidosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3536715
Disease: AA amyloidosis
AA amyloidosis 		0.020 Biomarker disease BEFREE To date, only in small case series preliminary clinical improvement have been shown with rituximab therapy for AA amyloidosis secondary to RA that is refractory to TNF-α inhibitors (TNF-i) therapy. 30400666 2018
CUI: C3536715
Disease: AA amyloidosis
AA amyloidosis 		0.020 Biomarker disease BEFREE Most common serious adverse events were sepsis and thrombotic events observed in 8 and 4 patients, respectively.Treatment with anti-TNFs may be associated with a higher survival rate compared with historic cohorts of AA amyloidosis, especially when started early with a lower serum creatinine level at baseline. 28834898 2017