TOP1, DNA topoisomerase I, 7150

N. diseases: 143; N. variants: 10
Disease: Intellectual Disability ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3714756
Disease: Intellectual Disability
Intellectual Disability 		0.010 GeneticVariation group BEFREE In addition, we identified differentially methylated CpG sites in LRP2BP (P-value=5.37 × 10<sup>-8</sup>) to be associated with intellectual disability (F70-79), in TOP1 (P-value=1.86 × 10<sup>-7</sup>) with behavioral disorders (F90-98), in NOSIP (P-value=5.12 × 10<sup>-8</sup>) with disorders of psychological development (F80-89) and in SEMA4B (P-value=4.02 × 10<sup>-7</sup>) with schizophrenia spectrum disorders (F20-29). 28850114 2017