TOP2A, DNA topoisomerase II alpha, 7153

N. diseases: 200; N. variants: 5
Disease: neurofibroma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027830
Disease: neurofibroma
neurofibroma 		0.020 Biomarker disease BEFREE The transcript levels of BRD4, EZH2 and TOP2A were determined in paired formalin-fixed paraffin-embedded (FFPE) neurofibroma/MPNST samples derived from the same NF1 patient and in a set of plexiform neurofibromas, atypical neurofibromas and MPNST. 28813519 2017
CUI: C0027830
Disease: neurofibroma
neurofibroma 		0.020 AlteredExpression disease BEFREE Among several deregulated genes found by cDNA microarray analyses, topoisomerase II alpha (TOP2A) was the most overexpressed gene in MPNSTs compared with benign neurofibromas. 14673046 2003