TP53, tumor protein p53, 7157

N. diseases: 2494; N. variants: 527
Disease: Keloid ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022548
Disease: Keloid
Keloid 		0.040 Biomarker disease BEFREE Mortalin (Mot) is a mitochondrial chaperone of the heat shock protein 70 family and it's pro-proliferative and anti-apoptosis functions could be associated with keloid pathogenesis, and blocking of mortalin and its interaction with p53 might be a potential novel target for the treatment of keloid. 29021584 2017
CUI: C0022548
Disease: Keloid
Keloid 		0.040 GeneticVariation disease BEFREE We conclude that the Pro allele of P53 Arg72Pro polymorphism is a risk factor for keloids in the Chinese population. 22843046 2012
CUI: C0022548
Disease: Keloid
Keloid 		0.040 AlteredExpression disease LHGDN Expression of p53 family in scars. 14757278 2004
CUI: C0022548
Disease: Keloid
Keloid 		0.040 GeneticVariation disease BEFREE To detect p53 DNA mutations in tissues and cultured fibroblasts from skin lesions of 7 patients with keloids. 9722726 1998