TP53, tumor protein p53, 7157

N. diseases: 2494; N. variants: 527
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026640
Disease: Mouth Neoplasms
Mouth Neoplasms
0.550 Biomarker group CTD_human Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin. 24224046 2013
CUI: C0026640
Disease: Mouth Neoplasms
Mouth Neoplasms
0.550 Biomarker group CTD_mouse Rapamycin prevents early onset of tumorigenesis in an oral-specific K-ras and p53 two-hit carcinogenesis model. 19435901 2009
CUI: C0026640
Disease: Mouth Neoplasms
Mouth Neoplasms
0.550 GeneticVariation group LHGDN Combined effects of the p53 codon 72 and p73 G4C14-to-A4T14 polymorphisms on the risk of HPV16-associated oral cancer in never-smokers. 18701437 2008
CUI: C0026640
Disease: Mouth Neoplasms
Mouth Neoplasms
0.550 GeneticVariation group LHGDN Association between the TP53 codon72 polymorphism and oral cancer risk and prognosis. 17306604 2007
CUI: C0026640
Disease: Mouth Neoplasms
Mouth Neoplasms
0.550 Biomarker group RGD Diabetes alters expression of p53 and c-myc in different stages of oral oncogenesis. 17595763 2007
CUI: C0026640
Disease: Mouth Neoplasms
Mouth Neoplasms
0.550 GeneticVariation group LHGDN Association of p53 and p21(CDKN1A/WAF1/CIP1) polymorphisms with oral cancer in Taiwan patients. 17595776 2007
CUI: C0026640
Disease: Mouth Neoplasms
Mouth Neoplasms
0.550 Biomarker group LHGDN The calcium-binding protein S100A2 interacts with p53 and modulates its transcriptional activity. 15941720 2005
CUI: C0026640
Disease: Mouth Neoplasms
Mouth Neoplasms
0.550 GeneticVariation group BEFREE These data suggest that p53 mutation may be a very early event in oral cavity tumor progression and demonstrate that pre-malignant lesions obtained from non-tobacco users do not exhibit p53 mutations. 7829258 1995